Xanthelasma Yellow Grain on the Eyelid

Yellow grains on the eyelid or xanthelasma are yellow plaques commonly found near the inner corner of the eye on the eyelid and often involve the upper eyelid.

This lesion is soft or semi-solid. They are usually bilateral, and all 4 eyelids can be involved.

Xanthelasma yellow grain lesions tend to progress and may become permanent.

Half of these lesions are associated with high levels of serum lipids or blood fats.

Some occur due to changes in the structure of lipoproteins and are associated with reduced HDL levels and are common in individuals with type 2 hyperlipidemia.

The prevalence of this lesion is higher in women than in men.

The age of onset of the disease is between 15 and 73 years, but its peak prevalence occurs in the 4th and 5th decades of life.

This lesion, which usually occurs singly, may remain stable or enlarge, and often individuals seek treatment for cosmetic reasons.

Diabetic individuals who are not under control and have increased blood fats due to this problem are also at risk of this lesion.

However, it is also seen in individuals with normal levels of blood fats but low levels of HDL or good cholesterol and other lipoprotein problems.

Treatment for xanthelasma yellow grain on the eyelid or xanthelasma

* Controlling diet and reducing serum lipid levels are essential in treating these lesions.

Although controlled diet plays a minor role in treating the lesion, it is effective in preventing it.

* Other treatment methods, including surgical removal, argon or carbon dioxide laser, chemical peeling, and cryotherapy, are used in its treatment:

– For small linear lesions, surgical removal is recommended as the scar fades along the eyelid line. If the lesion is large and completely removed, the likelihood of scarring is high, and the tissue tends to thicken.

– Carbon dioxide or argon laser is better than surgery due to its higher speed, better visibility, and lack of sutures, but it may lead to pigment changes and scarring.

– Chemical peeling, including monochloroacetic acid, dichloroacetic acid, and trichloroacetic acid, have had the best results, and minimal scarring remains.

– Cryotherapy or radiosurgery is used when these lesions are superficial, and repeated treatment is necessary, but there is a risk of hypopigmentation and scarring.

– Recurrence in this lesion is very common, and patients should follow up with medical and surgical treatment.

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